Jan-Ake Gustafsson Selected Research

Liver X Receptors

1/2017	Liver X Receptor β Is Involved in Formalin-Induced Spontaneous Pain.
8/2013	The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils.
8/2010	Estrogen-dependent gallbladder carcinogenesis in LXRbeta-/- female mice.
6/2010	Neuropathologic and biochemical changes during disease progression in liver X receptor beta-/- mice, a model of adult neuron disease.
1/2010	Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses.
11/2009	Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages.
6/2009	Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice.
3/2009	Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study.
2/2008	Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
12/2006	Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity.

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Jan-Ake Gustafsson Research Topics

Disease

45	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2002
35	Neoplasms (Cancer) 01/2018 - 01/2002
12	Insulin Resistance 06/2013 - 08/2002
10	Inflammation (Inflammations) 01/2017 - 12/2005
8	Carcinogenesis 08/2010 - 10/2003
8	Obesity 02/2010 - 11/2003
7	Cardiovascular Diseases (Cardiovascular Disease) 10/2009 - 01/2003
5	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 12/2004
5	Type 2 Diabetes Mellitus (MODY) 11/2020 - 08/2002
4	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2010 - 10/2002
4	Hepatocellular Carcinoma (Hepatoma) 04/2008 - 05/2002
4	Autoimmune Diseases (Autoimmune Disease) 07/2007 - 08/2004
3	Pain (Aches) 01/2019 - 08/2007
3	Hypertrophy 06/2010 - 05/2006
3	Atrophy 12/2009 - 03/2005
3	Colonic Neoplasms (Colon Cancer) 08/2009 - 09/2003
3	Body Weight (Weight, Body) 10/2008 - 05/2007
3	Adenocarcinoma 05/2008 - 06/2002
3	Hypertension (High Blood Pressure) 05/2006 - 01/2002
3	Carcinoma (Carcinomatosis) 05/2005 - 10/2003
2	Herpes Zoster 01/2015 - 11/2002
2	Pituitary Neoplasms (Pituitary Adenoma) 08/2011 - 04/2010
2	Colorectal Neoplasms (Colorectal Cancer) 08/2010 - 08/2009
2	Gliosis 06/2010 - 03/2005
2	Acute-Phase Reaction 02/2010 - 10/2004
2	Metabolic Diseases (Metabolic Disease) 02/2010 - 06/2008
2	Parkinson Disease (Parkinson's Disease) 10/2009 - 06/2002
2	Hypertriglyceridemia 10/2009 - 10/2006
2	Glucose Intolerance 11/2008 - 06/2008
2	Dementia (Dementias) 02/2008 - 01/2004
2	Stomach Neoplasms (Stomach Cancer) 01/2008 - 06/2002
2	Chronic Kidney Failure (Chronic Renal Failure) 09/2007 - 02/2004
2	Diabetes Mellitus 09/2006 - 12/2002
2	Bone Resorption 08/2006 - 01/2004
2	Hypoxia (Hypoxemia) 05/2006 - 09/2004
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2021
1	Epilepsy (Aura) 01/2021
1	Seizures (Absence Seizure) 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Liver Diseases (Liver Disease) 01/2019
1	Alcoholic Fatty Liver 01/2019
1	Liver Neoplasms (Liver Cancer) 01/2019
1	Non-alcoholic Fatty Liver Disease 01/2019

Drug/Important Bio-Agent (IBA)

58	Estrogen Receptor betaIBA 02/2014 - 01/2002
44	Estrogens (Estrogen)FDA Link 01/2021 - 01/2002
35	Estrogen Receptor alphaIBA 04/2010 - 06/2002
32	Estrogen ReceptorsIBA 01/2021 - 06/2002
13	Proteins (Proteins, Gene)FDA Link 02/2014 - 01/2002
13	Glucose (Dextrose)FDA LinkGeneric 06/2013 - 11/2003
12	Liver X ReceptorsIBA 01/2017 - 06/2005
11	LipidsIBA 01/2019 - 10/2002
10	Messenger RNA (mRNA)IBA 02/2014 - 10/2003
10	LigandsIBA 02/2014 - 06/2002
9	CholesterolIBA 02/2014 - 06/2005
8	Insulin (Novolin)FDA Link 06/2013 - 11/2003
7	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2002
7	Hormones (Hormone)IBA 04/2010 - 06/2005
7	Tamoxifen FDA LinkGeneric 08/2009 - 01/2002
6	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2010 - 11/2004
6	Estradiol (Delestrogen)FDA LinkGeneric 03/2009 - 01/2002
5	IsoflavonesIBA 01/2021 - 12/2005
4	Pharmaceutical PreparationsIBA 01/2021 - 07/2003
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 04/2010 - 08/2002
4	Triglycerides (Triacylglycerol)IBA 10/2009 - 03/2006
4	Progesterone Receptors (Progesterone Receptor)IBA 06/2004 - 09/2002
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2005
3	Formaldehyde (Formol)FDA Link 01/2017 - 09/2004
3	GlucocorticoidsIBA 01/2015 - 08/2002
3	Small Interfering RNA (siRNA)IBA 02/2014 - 01/2009
2	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 02/2014
2	AndrogensIBA 01/2021 - 02/2014
2	bisphenol AIBA 11/2020 - 01/2019
2	OxysterolsIBA 08/2013 - 02/2009
2	Phytoestrogens (Phytoestrogen)IBA 12/2010 - 08/2009
2	oxysterol binding proteinIBA 08/2010 - 04/2009
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 06/2010 - 09/2004
2	EnzymesIBA 01/2010 - 12/2002
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2009 - 07/2003
2	CytokinesIBA 11/2009 - 09/2005
2	Transcription Factors (Transcription Factor)IBA 01/2009 - 09/2004
2	NAD (NADH)IBA 10/2008 - 04/2008
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 09/2007 - 07/2004
2	Biological ProductsIBA 10/2006 - 03/2006
2	Caveolin 1IBA 05/2006 - 01/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 06/2005 - 10/2004
2	AntibodiesIBA 05/2005 - 09/2004
2	ParaffinIBA 05/2005 - 09/2004
2	Progesterone FDA LinkGeneric 01/2005 - 10/2003
2	Estrogen Receptor Modulators (Antiestrogen)IBA 09/2004 - 04/2004
2	Polychlorinated Dibenzodioxins (TCDD)IBA 07/2004 - 01/2004
1	Oxidoreductases (Dehydrogenase)IBA 01/2021
1	abirateroneIBA 01/2021
1	Finasteride (Propecia)FDA LinkGeneric 01/2021
1	enzalutamideIBA 01/2021
1	Endocrine DisruptorsIBA 11/2020
1	Voltage-Gated Sodium ChannelsIBA 01/2019
1	Analgesics (Analgesic Drugs)IBA 01/2017

Therapy/Procedure

16	Therapeutics 01/2021 - 01/2002
2	Drug Therapy (Chemotherapy) 06/2011 - 10/2006
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2017